During a play with bases loaded, if the runner from first base is thrown out at home while the other two runners score, what happens?

In this scenario, when the runner from first base is thrown out at home plate during a play with the bases loaded, it is considered a force play. For runs to score in this situation, the critical factor is whether the third out was a force out or not.

If the runner at home is put out as a result of a force play, then any subsequent runs scored by the other runners who crossed home plate before the third out is recorded do not count. This means that although the other two runners may have crossed home plate, their runs will not be counted because the third out was a force out. Therefore, the only runs that count in this context are those scored before the force out occurs.

In summary, since the runner from first is out due to being forced out at home, the conclusion is that no runs will count despite the apparent scoring by the other two runners.